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Definition Return to top
Lactic acidosis is when lactic acid builds ups in the blood stream faster than it can be removed. Lactic acid is produced when oxygen levels in the body drop.
Causes Return to top
The most common cause is intense exercise. However, it can also be caused by certain diseases, such as sepsis, respiratory failure, AIDS, cancer, and kidney failure.
Metformin, a common medicine used to treat diabetes, can also cause lactic acidosis. People taking this medicine should have their electrolyte levels checked 1 - 2 weeks after starting it.
Symptoms Return to top
Exams and Tests Return to top
Treatment Return to top
The primary treatment for lactic acidosis is correcting the underlying medical problem that causes the condition.
References Return to top
Oh MS. Evaluation of renal function, water, electrolytes and acid-base balance. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management of Laboratory Methods. 21st ed. Philadelphia, Pa: Saunders Elsevier; 2006: chap 14.
Seifter JL. Acid-base disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 119.Update Date: 11/16/2008 Updated by: Linda Vorvick, MD, Family Physician, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.