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Definition Return to top
Kuru is a disease of the nervous system.
Causes Return to top
Kuru is an extremely rare disease. It is caused by an infectious protein (prion) found in contaminated human brain tissue.
Kuru is found almost exclusively among people from New Guinea, who practiced a form of cannibalism in which the brains of dead people were eaten as part of a funeral ritual.
Kuru causes neurodegenerative changes similar to Creutzfeldt-Jakob disease. Similar diseases appear in cows as bovine spongiform encephalopathy (BSE), also called mad cow disease.
The main risk factor for kuru is eating human brain tissue, which can contain the infectious particles.
Symptoms Return to top
Symptoms of kuru include:
Difficulty swallowing and the inability to feed oneself lead to malnutrition or starvation.
It can take up to 30 years or even longer to develop symptoms (incubation period).
Exams and Tests Return to top
A neurological exam may show changes in coordination and walking ability.
Treatment Return to top
There is no known treatment for kuru.
Outlook (Prognosis) Return to top
Death usually occurs within 1 year after the first sign of symptoms.
When to Contact a Medical Professional Return to top
Call your health care provider if you have any walking, swallowing, or coordination problems. Kuru is extremely rare. Your doctor will rule out other neurological diseases.
References Return to topZeidler M. Prion diseases. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 442. Update Date: 12/3/2008 Updated by: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.