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Alternative Names Return to topGastric acid secretion test
Definition Return to top
The stomach acid test is used to measure the quantity and acidity of stomach contents.
How the Test is Performed Return to top
After not eating for a period of time, fluid is all that remains in the stomach. This fluid can be removed via a tube inserted through the esophagus (food pipe).
To test the ability of cells in the stomach to secrete acid, gastrin may be injected just under the skin, into a muscle, or into a vein. The stomach contents are then removed and analyzed.
Another test involves insulin-induced hypoglycemia. Enough insulin is given under the skin or through a vein to cause the blood sugar to decrease. This causes the vagus nerve to stimulate the release of gastrin. After a short time, the stomach contents are removed and analyzed.
How to Prepare for the Test Return to top
You will be asked not to eat or drink for 4 - 6 hours before the test.
How the Test Will Feel Return to top
You may notice some discomfort or a gagging feeling as the tube is passed through your nose or mouth, and down your esophagus.
Why the Test is Performed Return to top
This test may be used for a number of reasons:
Normal Results Return to top
Normally the volume of the stomach fluid is 20 to 100 mL and the pH is acidic (1.5 to 3.5). In some situations, these numbers are converted to actual acid production in units of milliequivalents per hour.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean Return to top
Risks Return to top
There is a slight risk of the tube being placed through the windpipe and into the lungs instead of through the esophagus and into the stomach. The health care provider will be sure the tube is correctly placed before continuing with the test.
If the test includes injection of insulin, there is a risk of bringing on symptoms of low blood sugar.
References Return to topJensen RT. Pancreatic endocrine tumors. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 205. Update Date: 11/2/2008 Updated by: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.